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ea0016p800 | Thyroid | ECE2008

Insulin resistance and oxidative stress induce advanced glycation end products formation in patients with clinical and subclinical hypothyroidism

Peppa Melpomeni , Hadjidakis Dimitrios , Alevizaki Maria , Dimitriadis George , Isari Georgia , Economopoulos Theofanis , Uribarri Jaime , Vlassara Helen , Raptis Sotirios A

Introduction: Advanced glycation end products (AGEs) formation is accelerated in various pathological conditions characterized by insulin resistance (IR) and/or increased oxidative stress (OS). Hypothyroidism overt (OH) or subclinical (SUH) is associated with a variety of metabolic disorders leading to IR and increased OS.Aim: To estimate the εN-carboxymethyl-lysine (CML) levels, in subjects with OH and SUH and seek f...

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ea0037ep624 | Obesity and cardiovascular endocrinology | ECE2015

Levels of advanced glycation end products (AGEs), AGE's receptor (sRAGE) and their relationship with cardiovascular risk factors in newly diagnosed type 2 diabetic patients

Villegas-Rodriguez Etzabel , Solorio-Meza Sergio , Fajardo-Araujo Martha Eugenia , Uribarri Jaime , Malacara Juan Manuel , Torres-Graciano Sofia , Garay-Sevilla Ma Eugenia

Diabetes is associated with a greatly increased risk of cardiovascular disease and the advanced glycation end products (AGEs) and their receptors play an important role in these complications.Objective: To study the association between AGEs and sRAGE levels with cardiovascular risk factors in obese and non-obese newly diagnosed type 2 diabetic patients.Material and methods: We conducted a cross-sectional study in subjects with type...

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Endocrine Abstracts

Insulin resistance and oxidative stress induce advanced glycation end products formation in patients with clinical and subclinical hypothyroidism

Levels of advanced glycation end products (AGEs), AGE's receptor (sRAGE) and their relationship with cardiovascular risk factors in newly diagnosed type 2 diabetic patients

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